Epileptic encephalopathies have been discussed in different publications but mainly in relation to childhood. However, recent years have shown an increase of the life expectancy and social integration of patients with epileptic encephalopathies. Although the treatment goals remain the same regardless of age, the clinical symptoms, EEG-abnormalities, mental and behavioural aspects, side effect profiles of antiepileptic drugs change over time, requiring evolving and sometimes innovative therapies. Moreover, the social issues are important to consider for the maintenance of consistency in the delivery of care. The present book covers the long-term evolution of epileptic encephalopathies in terms of clinical symptomatology, cognitive functions, treatment strategies and social care options. It will help clinicians, healthcare practitioners and social service professionals to understand better the natural history of epileptic encephalopathies, to identify specific management issues and to develop appropriate care strategies for this category of patients.