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Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) is a very rare genetic condition that was named in 2002. This handbook has been created to help educate and support all those impacted by HLRCC. HLRCC was formerly known as Reed's Syndrome. HLRCC can cause skin bumps, fibroids, and/or kidney cancer. It is important for people with HLRCC to understand their health risks and learn how to manage them. The description and management suggestions in this book have been assembled from physiciand and researchers all over the world with experience with HLRCC.